The AP1,JUN,P39 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to JUN. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The AP1,JUN,P39 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306)